i heard from a very reliable source (Starts with Void, ends in Main) that Wine(x) works better with a stock kernel.
I dont know how you would go building one of these, i know how to do it but its quite a long process.
By stock kernel i mean no patches (2.4.19, 2.4.20)
If you are willing to do this you could let us know and we can point you in the right direction (off to the MES FAQ.)