As long as the program doesn't link with elf, it should install on a Mac with little trouble. So, no Playstation emulators, assemblers, or core libs. Provided that you have all your dependencies met. The tricky part is getting your libtool in shape - I don't remember exactly how I did that, but now I can compile Linux programs. It will use the proper lib suffixes, use ppc arch, and write binaries big-endian. Xine, gtk, libxml2, freetype, php, mysql, apache, and gaim are just a sample of what I have built on my Mac.